Microdosing 101
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When Should You Avoid Microdosing?
- When you are younger than 18 years old
- When you are pregnant or breastfeeding
- In case of a mental or physical condition and/or illness
- If you have colour blindness
- In extreme cases of situations in your life that are beyond your control (for instance: grief)
- In combination with alcohol or other drugs
- In combination with lithium carbonate
- In combination with Tramadol
- When in the process of tapering off from antidepressants or anti-anxiety medication
What is microdosing?
Microdosing is the practice of consuming tiny, sub-perceptual amounts of a substance—such as psilocybin—for therapeutic and cognitive benefits. While these doses are too small to cause hallucinations, they may subtly enhance mood, creativity, focus, and overall mental well-being.
Users often report reduced anxiety and depression, heightened creativity, increased energy, and positive shifts in thought patterns—all while continuing their daily routines without disruption.
How does microdosing work?
Microdosing works by activating serotonin receptors, influencing mood, cognition, and neuroplasticity without causing hallucinations.
It reduces activity in the Default Mode Network (DMN), which may improve mental clarity, creativity, and emotional balance.
How does microdosing feel?
Microdosing produces subtle but noticeable effects.
Users often report enhanced mood, increased empathy, improved focus, and heightened creativity. It may also help facilitate a flow state, making tasks feel more effortless and engaging.
How much should I microdose ?
A standard microdose ranges from 100 mg (0.1 g) to 300 mg (0.3 g) of psilocybin mushrooms, taken every two to three days.
The ideal dose depends on individual sensitivity and goals. It’s best to start with 100 mg and adjust gradually for optimal effects.
How do I prepare for microdosing?
To prepare for microdosing, start by setting clear intentions.
Whether it’s enhancing focus, boosting creativity, or improving mood.
Choose a dosing schedule that suits your lifestyle, such as the Fadiman Protocol (one day on, two days off) or the Stamets Stack (four days on, three days off).
Begin with a low dose of 100 mg (0.1 g) and adjust gradually based on your experience.
Keeping a journal can help track effects and fine-tune your routine.
Maintaining a healthy lifestyle, managing stress, and ensuring proper sleep can enhance the benefits of microdosing.
- Set Your Intentions – Define your goals, such as improving focus, mood, or creativity.
- Choose a Schedule – Follow a proven protocol like the Fadiman (1 day on, 2 days off) or Stamets Stack (4 days on, 3 days off).
- Start with a Low Dose – Begin with 100 mg (0.1 g) and adjust gradually.
Comfort and safety: What things do you need to feel comfortable and safe? Who do you know that you can talk to if certain feelings or experiences arise?
When Is the Best Time to Microdose?
The best time to start microdosing is in the morning on an empty stomach to maximize absorption and benefits. Starting on a day without major obligations allows you to observe its effects without distractions. While some take microdoses later in the day, this may interfere with sleep.
Why Am I Feeling Anxiety After Microdosing?
Anxiety can occur if your dose is too high, as psilocybin affects serotonin levels. If this happens, try breathing exercises, meditation, or a short walk to ease discomfort. These effects are usually temporary and last up to 30 minutes—adjust your dose accordingly next time.
Why Should I Keep a Microdosing Journal?
Keeping a microdosing journal helps you track your experiences, emotions, and cognitive changes over time. Noting your dosage, mood shifts, and productivity levels can help you optimize your routine and understand how microdosing affects you personally.
What Should You Track While Microdosing?
Things you are
grateful for
Energy Level
Your current
mood
Sleep and exercise
Experiences/ Events
that are notable
Nutrition
Goals
The best way to take your microdose is by getting started on a day without any obligations like work, family, or social events. We recommend taking your microdose in the morning and on an empty stomach. In some cases, microdoses may be taken in the middle of the day, but doing so may cause difficulties sleeping later on.
What Are Reset Days in Microdosing?
Reset days are periods when you pause microdosing to prevent tolerance buildup and maintain effectiveness. These days also help you observe how your mind and body feel without microdosing, allowing for a clearer comparison of its effects on your mood, cognition, and overall well-being.
How Do You Find Your Ideal Microdose?
Finding the right microdose requires trial and adjustment, as effects vary between individuals. Start with a low dose (100 mg or 0.1 g) and gradually increase until you reach your desired effect. The goal is to feel subtle benefits without noticeable psychoactive effects.
